Acute Hemorrhagic Leukoencephalitis

A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)

Also Known As:

Hurst Syndrome; Syndrome, Hurst; Leukoencephalitis, Acute Hemorrhagic; Acute Hemorrhagic Encephalomyelitis; Encephalomyelitis, Acute Necrotizing Hemorrhagic; Encephalomyelitis, Hemorrhagic Necrotizing; Encephalomyelitis, Necrotizing Hemorrhagic; Hemorrhagic Encephalomyelitis, Necrotizing; Hemorrhagic Necrotizing Encephalomyelitis; Hurst's Disease; Leukoencephalitis Acuta Hemorrhagica; Leukoencephalitis, Subacute Hemorrhagic; Necrotizing Encephalomyelitis, Hemorrhagic; Acute Hemorrhagic Encephalomyelitides; Acute Hemorrhagic Leukoencephalitides; Acute Necrotizing Encephalitides; Acute Necrotizing Encephalitis; Disease, Hurst; Disease, Hurst's; Encephalitides, Acute Necrotizing; Encephalomyelitides, Acute Hemorrhagic; Encephalomyelitides, Hemorrhagic Necrotizing; Encephalomyelitis, Acute Hemorrhagic; Hemorrhagic Encephalomyelitides, Acute; Hemorrhagic Encephalomyelitides, Necrotizing; Hemorrhagic Encephalomyelitis, Acute; Hemorrhagic Leukoencephalitides, Acute; Hemorrhagic Leukoencephalitides, Subacute; Hemorrhagic Leukoencephalitis, Acute; Hemorrhagic Leukoencephalitis, Subacute; Hursts Disease; Leukoencephalitides, Acute Hemorrhagic; Leukoencephalitides, Subacute Hemorrhagic; Necrotizing Encephalitides, Acute; Necrotizing Encephalitis, Acute; Necrotizing Encephalomyelitides, Hemorrhagic; Necrotizing Hemorrhagic Encephalomyelitides; Subacute Hemorrhagic Leukoencephalitides; Subacute Hemorrhagic Leukoencephalitis; Encephalitis, Acute Necrotizing; Hurst Disease; Necrotizing Hemorrhagic Encephalomyelitis

Nervous System Diseases: 14178
- Demyelinating Diseases: 9131
  - CNS Demyelinating Autoimmune Diseases
    - Acute Disseminated Encephalomyelitis: 530
      - Acute Hemorrhagic Leukoencephalitis: 30
- Central Nervous System Diseases: 4213
  - Brain Diseases: 15694
    - Leukoencephalopathies: 1557
      - CNS Demyelinating Autoimmune Diseases
        Acute Disseminated Encephalomyelitis: 530
        Acute Hemorrhagic Leukoencephalitis: 30
- Autoimmune Diseases of the Nervous System: 1461
  - CNS Demyelinating Autoimmune Diseases
    - Acute Disseminated Encephalomyelitis: 530
      - Acute Hemorrhagic Leukoencephalitis: 30
Immune System Diseases: 4321
- Autoimmune Diseases: 34618
  - Autoimmune Diseases of the Nervous System: 1461
    - CNS Demyelinating Autoimmune Diseases
      - Acute Disseminated Encephalomyelitis: 530
        Acute Hemorrhagic Leukoencephalitis: 30

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